The D'Andrea Laboratory examines the molecular signaling pathways which regulate the DNA damage response in mammalian cells. Disruption of these pathways, by germline or somatic mutation, leads to genomic instability, cellular sensitivity to ionizing radiation, and defective cell cycle checkpoints...
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As director of the Division of Bone Marrow Transplantation and Immune Deficiency at the Cincinnati Children’s Hospital, Dr. Davies has helped pioneer significant advances in bone marrow transplantation to improve survival rates and reduce toxicity. She has led efforts to...
Dr. DeZern’s primary clinical and research interests are focused on bone marrow failure disorders. She has expertise in the diagnosis and treatment of myelodysplastic syndromes (MDS), aplastic anemia - both inherited and acquired, paroxysmal nocturnal hemoglobinuria (PNH), and acute leukemias.