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2024 Research Updates

Research is the answer to one day making FA a treatable, manageable disease. Here, you'll discover the most recent strides in FA research and activities funded by FCF. Every quarter, we'll bring you updates on newly funded grants, ongoing projects, and significant milestones.

DNA strands

What’s the most important relationship you have in the FA community?

I thought of my first FA friend, the many encounters I have shared with the FARF staff, board members, families, and all the friends I have made since rejoining the community a few years ago. I thought back on this...

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Alan D’Andrea Receives Lifetime Achievement Award

Read about Dr. D'Andrea's FARF-funded research projects At the 2019 FARF Scientific Symposium, Dr. D’Andrea was presented with the Lifetime Achievement Award for dedicating his career to the advancement of Fanconi anemia research. Dr. D’Andrea has been a pillar of...

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Central nervous system abnormalities in Fanconi anemia

Fanconi anemia (FA) is associated with progressive bone marrow failure, cancer predisposition, and multiple congenital abnormalities. Brain atrophy and other abnormalities of the brain have also been reported, although the cause of these abnormalities and recommendations for clinical care are...

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Advancements in Aldehyde Research

Aldehydes, including acetaldehyde and formaldehyde, can cause DNA damage by inducing DNA interstrand crosslinks, which cause damage to hematopoietic stem cells, leading to bone marrow failure and cancer in people with Fanconi anemia (FA). Exposure to aldehydes is inevitable and...

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Bone Marrow Failure: Clinical Trials

Pilot Study on Metformin A National Institutes of Health program project grant on Fanconi anemia (FA) led by Dr. Markus Grompe at Oregon Health & Science University identified that metformin (a drug approved by the FDA to treat type II...

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Research Update: Cancer in FA

Fanconi anemia (FA) is a hereditary disorder with a high predisposition to cancer, especially leukemia and squamous cell carcinoma (SCC). Head and neck squamous cell carcinoma (HNSCC) is the most common SCC diagnosed in people with FA. Diagnosis typically occurs...

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Join us at the upcoming #FCFSymposium and FA Adult Retreat September 19- 22 in Charlotte, North Carolina.
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