My lab’s vision for the next five years is to apply what we have learned to develop molecules that can alter FA protein behavior. These could be used to treat cancer or alter gene editing outcomes.
Fanconi Anemia Explained
What Is FA?
FA is a genetic disease caused by mutations in any of the known 23 genes (including genes such as BRCA1 and BRCA2) that play a role in the FA DNA repair pathway. FA is considered a cancer-predisposition or cancer-susceptibility disease. Decades of research have revealed that faulty DNA repair causes FA, and individuals with FA are much more likely to develop cancer at a young age.