Supported Research

CRISPR transcriptional screens for re-activation of HDR in FA patient-derived cells

2019 | Research Grant | ETH ZURICH

Amount Funded: $200,000

There is a great deal of excitement about the potential of CRISPR genome editing to treat disorders such as Fanconi anemia. But the mutations that cause FA also reduce the effectiveness of genome editing. Dr. Corn and colleagues will search for potential ways to re-activate genome editing in FA patient cells by searching through hundreds of thousands of interventions in parallel.

Researchers: Jacob Corn