A group of genes that works together to produce a person’s physical characteristics. Prior to the identification of the genes and genetic mutations that cause Fanconi anemia (FA), patients with the disease were classified into sub-categories known as complementation groups based on the patient’s cellular features. These complementation groups correspond to the various FA genes (e.g., individuals who belong to complementation group A have mutations in the FANCA gene, whereas individuals who belong to complementation group B have mutations in the FANCB gene).
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