Disease Information

Fanconi Anemia Explained

What Is FA?

FA is a genetic disease caused by mutations in any of the known 23 genes (including genes such as BRCA1 and BRCA2) that play a role in the FA DNA repair pathway. FA is considered a cancer-predisposition or cancer-susceptibility disease. Decades of research have revealed that faulty DNA repair causes FA, and individuals with FA are much more likely to develop cancer at a young age.

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Better Care Now

Clinical Care Guidelines

At Fanconi Cancer Foundation, we are in relentless pursuit of better care, better treatment, and ultimately, a cure for FA and FA-related cancers. Our clinical care guidelines are here as a resource for medical and care team providers who may never have crossed paths with FA before, in hopes they are able to provide better support for patients with FA.

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Knowledge Is Key

Cancer Awareness and Empowerment

Cancer can be daunting, and it’s natural to want to avoid dwelling on it. At FCF, we understand the weight of this concern for families affected by FA. That’s why we’re committed to partnering with the FA research and medical community to confront this challenge head-on. While experts work tirelessly towards solutions, we encourage you to stay informed without feeling overwhelmed.

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Stay Informed

Resource Library

Explore our library of educational materials and videos to empower individuals and families impacted by FA. Gain insights, guidance, and understanding to navigate FA’s complexities with more confidence.

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The Latest

News & Events

Behind the Research: Andrew Deans

My lab’s vision for the next five years is to apply what we have learned to develop molecules that can alter FA protein behavior. These could be used to treat cancer or alter gene editing outcomes.

Inspiration Through Education: Omar’s Journey with Fanconi Anemia

In a world where every day presents new challenges, my 11-year-old son, Omar, from Oman, stands out for his resilience and eagerness to raise awareness about Fanconi anemia. Diagnosed at just five years old, we truly believe his journey is a testament to hope and the strength of the human spirit.

Breaking Ground in Cancer Research: Introducing the Fanconi Cancer Foundation-AACR NextGen Grant

That's why we're thrilled to announce the launch of the Fanconi Cancer Foundation-AACR NextGen Grant for Transformative Cancer Research, a flagship funding opportunity in partnership with the American Association for Cancer Research (AACR).