Clinical Trials and Research Opportunities
Current Clinical Trials
Metformin Hydrochloride in Preventing Oral Cancer in Patients With an Oral Premalignant Lesion
Sponsor: National Cancer Institute
PI: Scott Lippman, MD
Open: June 2016
FA patients with a history of oral lesions may be eligible for this trial.
Study of Pembrolizumab (MK-3475) for High Risk Oral Intra-Epithelial Neoplasias
Sponsor: M.D. Anderson Cancer Center
PI: William N. William, Jr., MD
Estimated open date: March 2017
FA patients who have not had a transplant and who have a history of oral lesions may be eligible to apply for this trial.
Both of these trials are for patients with histories of oral premalignant lesions. FA patients with a history of oral premalignant lesions are advised to contact the trial coordinators to determine whether they are eligible for enrollment.
The Fanconi Anemia Research Fund publishes the FA Courier for the following purposes:
- To keep families informed of research projects and clinical trials in which they may be interested.
- To encourage FA patients to respond to the urgent need for research materials for FA research projects. The materials needed include blood, cord blood, bone marrow, and samples of tumors. Research materials also include the participation by FA patients or relatives in the collection of data about the disease, such a completing questionnaires about FA.
Current issue: FA Courier #20
Many patients undergo periodic CBCs and bone marrow aspirations. At that time, it is possible that the FA patient's physicians can draw a small additional amount to send to a research laboratory without causing any harm or additional discomfort to the FA patient. Whenever a tumor is biopsied or removed, it is possible to donate a small sample for research purposes.
Researchers don't need samples just from FA patients. Some studies request samples from relatives of FA patients, so family members of patients are urged to respond to these requests as well.
Researchers studying FA are encouraged to submit their projects to the FA Courier if they have a need for FA-specific research materials to complete the project.
Information provided in this publication about medications, treatments, or products should not be construed as medical instruction or scientific endorsement. Always consult your physician before taking any action based on the information from this website.